Its initial lineup consisted of Paul Banks (vocals and guitar), Carlos Dengler (bass and keyboards), Daniel Kessler (guitar) and Greg Drudy (drums). In 2000, Drudy left the band, being replaced by Sam Fogarino.
Their debut album, Turn on the Bright Lights, released in 2002, featured some of the band's biggest hits, such as "NYC", "PDA" and "Obstacle 1". Antics, the second album, was released in 2004. Three years later, Interpol released Our Love To Admire, the third studio album.
In 2010, Interpol released an eponymous album, the fourth of the band's career. After this release, Carlos Dengler left the group. Their fifth album, El Pintor, arrived in September 2014. In 2018, the band released Marauder, an album produced by Dave Fridmann. The band returned in 2022 with The Other Side of Make-Believe.